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Stem cells are able to produce potent anti-inflammatory agents named cytokines that trigger a faster course in skin regeneration.

These small molecules are able to improve scar formation by decreasing the stress levels in skin cells and by promoting skin cell proliferation and differentiation.

Totipotent stem cell metabolome Turmeria Zen-CPRCF

Turmeria Zen-CPRCF provides the restoration of inflammatory levels, by reducing cytokine production in inflamed cells, significantly increases hydration rate and accelerates wound healing up to 72%.

In the healing process the use of stem cells also inhibits the development of keloids and fibrolasts, responsible for hypertrophic scar formation.

Wound healing properties (Scratchtest)

  • TZkcell accelerated the healing process up to +72% higher at 24h and up to 63% at 48h compared to baseline conditions
  • The enhancer effect at 24h was higher than 10% FBS.

The use of bioactive metabolites of totipotent stem cells in KELO.CELL Biogel provides more effective and safer results than Dexamethasone on the inflammatory process.

Anti-inflammatory activity in human monocytes

  • Turmeria Zen-CPRCF stem cells completely restored TNF-α levels from inflamed cells.
  • The effect was very potent at all tested dose stretching up to -97%.
  • Dexamethasone restoration levels was up to -56%.

The Stem Cells efficacy in the inflammation process

The use of stem cells decreases the levels of cytokines that are naturally produced by our body during the inflammation process.

Turmeria Zen-CPRCF has anti-oxidant effect by inhibiting the release of free radicals (hydrogen peroxide).

Anti-Inflammatory

NF-κβ
TNF-α
MMP-1 and MMP-3
IL-1β IL-6 IL8
COX-2

Antioxidant

Free radicals
DNA damage
Lipid peroxidation
GSH

Other Effects

Collagen content
Facial elasticity
Skin fungal

Kelo.Cell Biogel

The unique biogel that combines both of benefits of silicone products and the extraordinary potential of bioactive totipotent stem cells.
This revolutionary formulation dries quickly and can effectively reduce the appearance of scars, decrease inflammation and promote tissue regeneration.
Take a look at real results of silicone scar treatment!
See Before/After results